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Nitrazolam is a benzodiazepine that has been sold online as a designer drug.
It is closely related to clonazolam, only differing by the removal of a chlorine group at the benzene ring. A study in mice indicated that nitrazolam can be several times more potent than diazepam as an antagonist of electroshock-induced tonic-extensor convulsions but less potent than diazepam at preventing the righting reflex.
Nitrazolam has been used as an example compound to demonstrate the microscale synthesis of reference materials utilizing polymer-supported reagents. In the UK, nitrazolam has been classified as a Class C drug by the May 2017 amendment to The Misuse of Drugs Act 1971 along with several other designer benzodiazepine drugs.
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